Poly rc -binding protein 1

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August undefined, 2024

WebJan 29, 2024 · The hepatitis C virus (HCV) co-opts numerous cellular elements, including proteins, lipids, and microRNAs, to complete its viral life cycle. The cellular RNA-binding … WebFeb 28, 2024 · 17 and microRNAs – to complete its viral life cycle. The cellular RNA-binding protein poly(rC)-18 binding protein 1 (PCBP1) had previously been reported to bind the …

Iron Chaperone Poly rC Binding Protein 1 Protects Mouse Live ...

WebSep 11, 2003 · Here, we show that members of the poly (rC) binding protein family, poly (rC) binding protein 1 (PCBP1), poly (rC) binding protein 2 (PCBP2) and hnRNPK were able to activate the IRES in vitro up ... WebMay 1, 2024 · Poly(rC)-binding protein 1 (PCBP1) is a multifunctional RNA-binding protein that plays various roles in gene transcription, RNA regulation, and iron chaperone [8, 9]. … how far is bonita springs from cape coral fl

Iron Chaperone Poly rC Binding Protein 1 Protects Mouse Liver From Li…

WebA protein covalently linked to poliovirus genome RNA. Proc Natl Acad Sci U S A. 1977 Jan; 74 (1):59–63. [PMC free article] [Google Scholar] Leffers H, Dejgaard K, Celis JE. Characterisation of two major cellular poly(rC)-binding human proteins, each containing three K-homologous (KH) domains. Eur J Biochem. 1995 Jun 1; 230 (2):447–453. WebMay 11, 2024 · Poly(rC)-binding protein1 (PCBP1) is an RNA-binding protein that regulates mRNA stability, splicing, and translation. PCBP1 is a tumor suppressor and can inhibit the translation of several oncogenic genes. ... Poly(rC) binding protein 1 represses the translation of STAT3 through 5' UTR. @article{Li2024PolyrCBP, title={Poly ... WebMay 21, 2024 · Poly rC binding protein 1 (PCBP1) is a multifunctional protein that serves as a cytosolic iron chaperone, binding and transferring iron to recipient proteins in … how far is bonita springs from fort myers fl

Poly(rC)-binding protein 1 represses ferritinophagy-mediated ...

23983 - Gene ResultPcbp1 poly(rC) binding protein 1 [ (house …

WebFeb 5, 2024 · The interaction of HIV-1 CA with human cellular poly (rC) binding protein 1 (PCBP1, hnRNP E1: heterogenous nuclear ribonucleoprotein E1) is identified by yeast two … WebJul 1, 2024 · Poly(rC)-binding protein 2 (PCBP2) is an RNA-binding protein that is characterized by its ability to interact with poly(C) with high affinity in a sequence-specific manner. PCBP2 contains three K homology domains, which are consensus RNA-binding domains that play a role in recognizing and combining with RNA and DNA. hifly hf201 155/65r14 75tWebMay 10, 2024 · Objective To monitor the phosphorylation modifications and cellular localization of poly(rC)-binding protein-1 (PCBP1) during the cell cycle progression of Hela cells. Result Hela cells highly synchronized at five different phases from interphase to mitosis were obtained. Using mitotic phosphoprotein-specific monoclonal antibody MPM … hifly hf201 195/50/15

"WebMar 3, 2009 · The poly(C)-binding proteins (PCBPs) are characterized by high affinity for, and sequence-specific interaction with polycytosine, poly(C). In mammalian cells, these PCBPs belong to one of two subsets: hnRNP K/J, or the alpha-complex proteins (e.g., PCBP1-4) []. hnRNP K, PCBP1, and PCBP2 have been studied in the greatest detail.The latter two … " - Poly rc -binding protein 1

Poly rc -binding protein 1

Advances in poly(rC)-binding protein 2: Structure, molecular function …

WebFeb 28, 2024 · The hepatitis C virus (HCV) co-opts a number of cellular elements – including proteins, lipids, and microRNAs – to complete its viral life cycle. The cellular RNA-binding protein poly(rC)-binding protein 1 (PCBP1) had previously been reported to bind the HCV genome 5’ untranslated region (UTR), but its importance in the viral life cycle has … WebAug 21, 2024 · However, splicing factors can also play negative roles in tumorigenesis. In the current review, we focus on splicing factor poly(rC)-binding protein 1 (PCBP1), a novel tumor suppressor that is characterized by downregulation in many cancer types and shows inhibition of tumor formation and metastasis.

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WebJan 20, 2024 · We found a C-rich element (CRE) in mu-opioid receptor (MOR) 3'-untranslated region (UTR) to which poly (rC) binding protein 1 (PCBP1) binds, resulting in MOR mRNA … Webpoly(rC) binding protein 1. Synonyms: HNRPE1, HNRPX, hnRNP-E1, hnRNP-X. Species: Human PCBP1 (5093), Mouse Pcbp1 (23983), Rat Pcbp1 (500242), Horse... Summary: …

WebFeb 26, 2024 · Poly(rC) binding protein 2 (PCBP2), a 39 kDa protein, is a member of the α-globin mRNP stability complex [7, 8]. As a generally known RNA-binding protein, PCBP2 possesses three K homology domains, which are the main RNA-recognition regions [ 9 , 10 ] . WebPoly (rC)-binding protein1 (PCBP1) is an RNA-binding protein that regulates mRNA stability, splicing, and translation. PCBP1 is a tumor suppressor and can inhibit the translation of …

WebCommon to processing body (P body) and stress granule. K12889 PCBP1; poly (rC)-binding protein 1. Spliceosome [BR: ko03041] Common components. Common spliceosomal components. hnRNP proteins. K12889 PCBP1; poly (rC)-binding protein 1. BRITE hierarchy. WebMar 19, 2024 · PCBP1 is an intron-less gene encoding the 356 amino acid poly(rC) binding protein 1, which contains three K-Homology (KH) domains and two nuclear localization signals. The mutations predominantly ...

WebThe hepatitis C virus (HCV) co-opts numerous cellular elements, including proteins, lipids, and microRNAs, to complete its viral life cycle. The cellular RNA-binding protein, poly(rC)-binding protein 1 (PCBP1), was previously reported to bind to the 5′ untranslated region (UTR) of the HCV genome; however, its importance in the viral life cycle has remained …

WebDec 8, 2024 · Poly(rC) Binding Protein 1 Represses the Translation of STAT3 through 5' UTR. Li Z, Wang X, Jia RLi Z, et al. Curr Gene Ther, 2024. PMID 35549870; Poly(rC)-Binding … how far is bonita springs from naplesWebPCBP1. Poly (rC)-binding protein 1 is a protein that in humans is encoded by the PCBP1 gene. [5] This intronless gene is thought to have been generated by retrotransposition of a … how far is bonita springs from naples floridaWebFeb 26, 2024 · Poly(rC) binding protein 2 (PCBP2) is an RNA-binding protein that contributes to mRNA stabilization, translational silencing and enhancement and it has been implicated as a promoter of gastric cancer growth. In the present study, ... how far is bonita springs from miami flWebPoly(rC)-binding protein 1 1 publication. Alternative names. Alpha-CP1 1 publication. Heterogeneous nuclear ribonucleoprotein E1 (hnRNP E1) Nucleic acid-binding protein … hi fly guy book activitiesWebPoly(rC) binding protein 1 (PCBP1) is … Coxsackievirus B3 (CVB3) is a positive single-strand RNA virus causing myocarditis, pancreatitis and meningitis. During CVB3 infection, … how far is bonita springs from tampaWebFeb 28, 2024 · 17 and microRNAs – to complete its viral life cycle. The cellular RNA-binding protein poly(rC)-18 binding protein 1 (PCBP1) had previously been reported to bind the HCV genome 5´ 19 untranslated region (UTR), but its importance in the viral life cycle has remained unclear. 20 Herein, we aimed to clarify the role of PCBP1 in the HCV life cycle. how far is bonita springs from ft myers flWebDec 8, 2024 · The iron chaperone and nucleic acid-binding activities of poly (rC)-binding protein 1 are separable and independently essential. RNA-Binding Proteins PCBP1 and … how far is boone from des moines