WebGene ID: 127770328, updated on 29-Nov-2024. Summary Other designations. lysine-specific histone demethylase 1 homolog 3-like Web11 apr. 2024 · Histone modification-related enzymes thought to be associated with prostate cancer progression include histone methyltransferase EZH2 , lysine-specific demethylase 1 (LSD1) , histone methyltransferase SET9 , and others.
Lysine-specific histone demethylase 1 inhibition promotes reprogramming ...
Web15 oct. 2024 · Lysine-specific histone demethylase 1 (KDM1A or LSD1) belongs to the amine oxidase superfamily of flavin adenine dinucleotide-dependent enzymes. LSD1 is a component of transcriptional repressor complexes that can demethylate histone H3 Lys 4 (H3–K4) (Perillo et al., 2024; Shi et al., 2004; Yang et al., 2007). A recent study found … WebLysine specific demethylase 1 (LSD1, also known as KDM1) is a histone modifying enzyme that regulates the expression of many genes important in cancer progression … communication a thing of the past
Lysine-Specific Demethylase 1 Promises to Be a Novel Target in …
WebThe Histone Lysine-specific Demethylase 1 Inhibitor, SP2509 Exerts Cytotoxic Effects against Renal Cancer Cells through Downregulation of Bcl-2 and Mcl-1. Journal of Cancer Prevention 2024, 25 (2) , 79-86. Webprotein LSD1/KDM1 [for lysine-specific demethylase 1, later renamed lysine (K) demethylase 1 to standardize nomenclature; also known as AOF2] (see Table 2) was identified as the first histone ... WebTreatment and control of schistosomiasis still rely on only one effective drug, praziquantel (PZQ), and due to mass treatment, the increasing risk of selecting for schistosome strains that are resistant to PZQ has alerted investigators to the urgent need to develop novel therapeutic strategies. The histone-modifying enzymes (HMEs) represent promising … communication at eye level