Immunometabolism in the single-cell era
Witryna28 mar 2024 · Verberk et al. describe accessible, stepwise workflows for profiling mouse and human macrophage immunometabolism. Their toolbox integrates distinct metabolic and functional immune assays utilizing a 96-well plate format, providing a practical, semi-high-throughput approach to assess cellular metabolism of immune cells. Witryna14 mar 2024 · Artyomov MN, Van den Bossche J (2024) Immunometabolism in the single‐cell era. Cell Metab 32: 710–725 [PMC free article] ... (2024) Single cell metabolomics: a future tool to unmask cellular heterogeneity and virus‐host interaction in context of emerging viral diseases. Front Microbiol 11: 1152 [PMC free article] …
Immunometabolism in the single-cell era
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Witryna15 kwi 2024 · Artyomov, M. N. & van den Bossche, J. Immunometabolism in the single-cell era. Cell Metab. 32 , 710–725 (2024). Article CAS PubMed PubMed Central Google Scholar Witryna30 wrz 2024 · → I am an accomplished researcher equipped with specialist expertise in metabolic disease and host-pathogen interactions, gained throughout my PhD and postdoctoral training. → As demonstrated by my publication record, I have a deep knowledge of tissue engineering, epigenetics, metabolism, immunity, and single …
Witrynaimmunometabolism, the technologies become more limited. Commonly used Seahorse XF analysis provides detailed real-time measurements of metabolic activity but requires an abundance of cells that is often not achievable, especially in the single-cell era. A preliminary picture of cellular metabolism can be obtained by single-cell Witryna13 kwi 2024 · Immunometabolism the CyTOF way. In this issue of Immunity, Levine et al. report a CyTOF-based approach for the analyses of CD8 + T cells metabolic …
Witryna3 lis 2024 · Single-Cell Immunometabolism of Treg/Th17 Cell As every cell resides in a unique environment, no cell within our body is completely identical metabolically, … Witryna13 kwi 2024 · In the past few years, several studies have demonstrated that cellular metabolic function is drastically altered in OA and aberrant immunometabolism may be a key feature of many phenotypes of OA 7.
Witryna27 wrz 2024 · Metabolism as a driver of immunity. Immune cell activation initiates a programme of cell growth and differentiation, often coupled to proliferation. By the 1970s it was known that lymphocytes ...
Witryna14 sty 2024 · Single epithelial cells, called enterocytes, tightly connected to each other, cover the internal surface of our intestinal mucosa. These cells provide a barrier that selectively regulates the exchanges between the inner and the outer environment of luminal toxins, antigens as well as the absorption of nutrients and water, by using both ... bipper 5 places occasionWitryna14 kwi 2024 · The view that most female mammals incapacitated oocyte production at birth has been debated in recent years by the finding that postnatal ovaries of mouse exist mitotically active germ cells [].Recently, multiple research teams including us, have used a variety of methods to prove the existence of OGSCs, such as stem cell culture … bip people portalWitryna31 mar 2024 · Recent research about immunometabolism has contributed to the realization that stimuli and changes in the environment macrophages and DCs are exposed to, eventually converge into alterations in their metabolic properties. ... However, recent advances in single-cell technologies, such single-cell RNA sequencing and … bipp class near meWitryna15 kwi 2024 · Artyomov, M. N. & van den Bossche, J. Immunometabolism in the single-cell era. Cell Metab. 32 , 710–725 (2024). Article CAS PubMed PubMed Central … bipp earWitrynaFigure 1 CTRP9 treatment promotes macrophages efferocytosis in vitro and in vivo. (A) TAMRA-labeled apoptotic cells were incubated with FITC-labeled macrophages at 10:1 ratio for 45 min.The unengulfed ACs were removed by rinsing, and the macrophages were detached from the plate for flow cytometric analysis of TAMRA + FITC + cells, … bipp consultingWitrynaBut with the emergence of single-cell applications, researchers can now estimate the metabolic state of individual immune cells in clinical samples. Here, we review these single-cell techniques and their ability to validate common principles in immunometabolism, while also revealing context-dependent metabolic … bipper 5 placesWitryna29 wrz 2024 · This review highlights the leading techniques used to study immunometabolism and their development, the immune cells at the maternal-fetal interface and their metabolic features required for the implementation of their functions, and explores the interaction between immunometabolicism and pregnancy regulation … bip peche