Drugs that potentiate warfarin
WebWarfarin (Coumadin) is the most frequently prescribed oral anticoagulant, the fourth most prescribed cardiovascular agent and the overall eleventh most prescribed drug in the United States, 1 with ... WebPharmacokinetic mechanisms for drug interactions with warfarin sodium are mainly enzyme induction, enzyme inhibition, and reduced plasma protein binding. ... Hepatic impairment can potentiate the response to warfarin through impaired synthesis of clotting factors and decreased metabolism of warfarin. Conduct more frequent monitoring for ...
Drugs that potentiate warfarin
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WebInhibition or potentiation of warfarin metabolism. Broad-spectrum penicillins. ... Buckley NA, Dawson AH, Drug interactions with warfarin. Med J Austr 1992; 157: 479–483. … WebPotentiation of warfarin by tetracycline. Potentiation of warfarin by tetracycline. Potentiation of warfarin by tetracycline Am J Hosp Pharm. 1980 Dec;37(12):1620, 1625. Authors L K Westfall, D L Mintzer, T H Wiser. PMID: ... Drug Synergism Female Humans ...
WebDrug points: Potentiation of warfarin anticoagulant activity by miconazole oral gel. Miconazole is a synthetic imidazole with broad spectrum activity against pathogenic fungi … WebJun 13, 2005 · A list of the vitamin K content in foods can be found at www.nal.usda.gov/fnic/foodcomp. Other potential inhibitors of warfarin include soy milk, seaweeds, ginseng and large amounts of avocado. Some surprising things that can increase the action of warfarin include mango, grapefruit juice and a variety of herbal supplements.
WebThese medications can all be taken regularly without regular lab testing and are often used when warfarin isn’t an option. One medication, dabigatran, is a thrombin inhibitor similar to the IV thrombin inhibitors listed earlier. Other medications, apixaban, edoxaban and betrixaban, are all inhibitors of factor Xa (10-A), a key clotting component. WebNational Center for Biotechnology Information
WebMay 1, 2024 · Fluvastatin (Lescol), lovastatin (Mevacor), rosuvastatin (Crestor), and simvastatin (Zocor) inhibit warfarin metabolism by the inhibition of CYP2C9, leading to increased warfarin concentrations...
WebDrugs such as cholestyramine can reduce the anticoagulant effect of warfarin by reducing its absorption. Other drugs potentiate the anticoagulant effect of warfarin by inhibiting its clearance, whereas some drugs may inhibit the anticoagulant effect … differential diagnosis of acute coughWebIn contrast, drugs such as cimetidine and omeprazole, which inhibit clearance of the R-isomer, potentiate the PT only modestly in patients treated with warfarin. 26,29,31 … differential diagnosis of ankle painWebDanshen is a herbal medicine often used for various complaints, particularly cardiovascular, in the Chinese community. The active ingredients of danshen, tanshinones and … differential diagnosis of acute cholecystitisWebFour significant drug interactions with warfarin are: fluconazole, amiodarone, sulfamethoxazole/trimethoprim, and metronidazole. Potentially life-threatening … format on pasteWebin patients on stable warfarin therapy (480 mL/day cranberry juice)48 or of thromboplastin time in healthy volunteers (600 mL/day cranberry juiceE).32 See also note E. Monitor (low level of risk at typical doses). Dong Quai Angelica polymorpha Antiplatelet and anticoagulant drugs May potentiate effect of drug. Herb Alone and with Drug format on powerpointWebMany of the drugs identified as potentiating warfarin’s effect are known inhibitors of CYP 2C9, including amiodarone, fluconazole, fluvastatin, fluvoxamine, isoniazid, lovastatin, … differential diagnosis in physical therapyWebFeb 1, 1997 · There was no other change in the patient's drug treatment. Two previous cases have been reported of miconazole oral gel potentiating the action of warfarin.4 5 Potentiation has also occurred with the oral anticoagulants nicoumalone6 7 and phenindione.8 Together they indicate that the oral gel may be sufficiently absorbed to … formato notas word