Cisplatin and hydration
WebIntroduction: Cisplatin, a platinum-based antineoplastic agent, is the cornerstone for the treatment of many malignancies. Nephrotoxicity is the primary dose-limiting toxicity, … WebHyponatremia of grade 3 or above developed in 30.7% of the generic CDDP group compared to 15.1% of the brand-name CDDP group ( P =0.011). Multivariate analysis showed that the use of generic CDDP increased the incidence of hyponatremia (odds ratio =5.661, 95% confidence interval =1.403–22.839; P =0.015). Conclusion: Oncologists …
Cisplatin and hydration
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WebThis regimen must be administered by a clinician trained in the use of chemotherapy, who should use independent medical judgment in the context of individual circumstances to make adjustments, as necessary. IV: intravenous; CBC: complete blood count; GFR: glomerular filtration rate. WebDec 16, 2024 · IntroductionCisplatin, a chemotherapeutic drug, is widely used for the treatment of various malignant tumors with good effects. However, cisplatin-induced …
WebCisplatin for injection is indicated for the treatment of advanced bladder cancer. 2 DOSAGE AND ADMINISTRATION . 2.1 Hydration and Anti-Emetic Treatment . Patients …
WebSep 4, 2013 · Cisplatin was administered with pre- and post-hydration containing 10 mEq of potassium chloride in 500 ml of fluid over a 60-min period. Immediately before the administration of cisplatin, mannitol (20%, 200 ml) was administered as forced diuresis over 30 min. And magnesium sulfate (8 mEq) was added to pre-hydration. Results WebApr 12, 2024 · AKI, present in 20–30% of patients’ cisplatin exposed, is usually non-oliguric. Moreover, urinalysis may detect glycosuria and a low-grade proteinuria. AKI-related cisplatin may also be associated with tubulopathies, such as Fanconi-like syndrome, hypomagnesemia, salt-loosing syndrome and distal renal tubular acidosis . Tubular …
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WebMannitol for the prevention of cisplatin-induced nephrotoxicity: A retrospective comparison of hydration plus mannitol versus hydration alone in inpatient and outpatient regimens at a large academic medical center J Oncol Pharm Pract. 2024 Sep;23 (6):422-428. doi: 10.1177/1078155216656927. Epub 2016 Jun 27. Authors ctrl + 2 not workingWebOct 19, 2024 · Staying Hydrated Before Moderate to High-Dose Cisplatin. This information will help you hydrate yourself to get ready for your cisplatin chemotherapy. Cisplatin can … ctrl 5 in wordWebOct 19, 2024 · This information will help you hydrate yourself to get ready for your cisplatin chemotherapy. Cisplatin can affect your kidneys. To keep your kidneys from getting damaged, you’ll need to drink plenty of liquids before you get cisplatin chemotherapy. earth touch bend oregonWebApr 12, 2024 · Cisplatin is a platinum-based chemotherapy agent that currently used as front-line therapy in the treatment of various solid organ cancers, including head and neck, lung, testis, ovary, breast, bladder cancer and sarcoma [1–7]. The therapeutic effects of cisplatin are significantly improved by dose escalation. earth total surface areaWebApr 27, 2024 · Currently, the ABC02 regime includes a long hydration schedule based on previous use of high doses of cisplatin and perhaps historically the lack of efficacious antiemetics. Cisplatin is often associated with severe nausea and … ctrl+5 in ms wordWebCisplatin is a chemotherapy drug used to treat testicular, ovarian, bladder, head and neck, lung and cervical cancer. It may also be used to treat other cancers. It is best to read this information with our general information about chemotherapy and the … earth touch gardens huntsville alWebFeb 16, 2016 · In this study, we assessed nephrotoxicity in daily practice among patients treated with high-dose cisplatin (100 mg/m 2 on days 1, 22, and 43), concurrently with chemoradiotherapy (CCRT) and the impact on treatment modifications. Methods: 208 patients with advanced-stage malignancies of the head and neck region were evaluated. ctrl + 5 artinya