WebThe Appel reaction is an organic reaction that converts an alcohol into an alkyl chloride using triphenylphosphine and carbon tetrachloride. The use of carbon tetrabromide or bromine as a halide source will yield alkyl bromides, whereas using carbon tetraiodide, methyl iodide or iodine gives alkyl iodides.The reaction is credited to and named after … The Borsche–Drechsel cyclization is a chemical reaction used to synthesize tetrahydrocarbazoles by the acid-catalyzed cyclization of cyclohexanone arylhydrazones. The reaction was first described by Edmund Drechsel in 1888 and by Walter Borsche in 1908. Borsche–Drechsel cyclization is the … See more The reaction has been described in the literature as proceeding in a manner similar to the Fischer indole synthesis. Here, the acid-catalyzed proton transfer first converts the cyclohexanone phenylhydrazone 1 … See more • Bucherer carbazole synthesis • Fischer indole synthesis See more
Borsche–Drechsel cyclization Semantic Scholar
WebBorsche-Drechsel reaction, is an acid-catalyzed cyclization reaction that was firstly studied by Edmund Drechsel and Walter Borsche [36, 37]. The reaction was generally used for the synthesis of ... WebJan 26, 2006 · Borsche-Drechsel reaction, is an acid-catalyzed cyclization reaction that was firstly studied by Edmund Drechsel and Walter Borsche [36, 37]. The reaction was generally used for the synthesis of ... flexible shaft carving tools
Isomeric ellipticines. Part 1. Synthesis of two linear isomers of …
WebThe Borsche-Drechsel cyclization, also known as Borsche carbazole synthesis, is the two-step conversion of phenyl hydrazine and cyclohexanone derivatives to the … WebFischer Indole Synthesis. The conversion of aryl hydrazones to indoles; requires elevated temperatures and the addition of Brønsted or Lewis acids. Some interesting enhancements have been published recently; for … WebJan 1, 2003 · Jinzhong Yao. An efficient base-catalyzed protocol for the synthesis of benzothiophene is described. The reaction proceeds via base-promoted propargyl-allenyl … flexible shaft tube brushes